NCT03733509

Intraoperative Direct vs Postoperative Ultrasound Guided Adductor Canal Nerve Block After Total Knee Arthroplasty

Intraoperative Direct Adductor Canal Nerve Block Versus Post Operative Ultrasound Guided Adductor Canal Nerve Block in Total Knee Arthroplasty: a Double-blind Randomized Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 121 (actual)
• Sponsor: Pontificia Universidad Catolica de Chile · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

This study compares analgesic effect between two techniques of adductor canal nerve block after total knee arthroplasty. The first group of the patients will receive intraoperative adductor canal nerve block; and the other group post operative ultrasound guided adductor canal nerve block. Investigators will measure postoperative opioid consumption, pain management and rehabilitation goals.

Detailed description

Total knee arthroplasty (TKA) is a successful alternative to treat late stage knee osteoarthritis (OA). Pain management has been one of the main focuses of postoperative care. Most surgeons prefer a comprehensive multimodal approach including preoperative pharmacological treatment, intraoperative infiltration with complex drug mixes and postoperative peripheral nerve block. The most common postoperative nerve block alternative is the proximal femoral nerve block (FNB) which has shown improvements on postoperative pain measured by reduced opioid consumption and decreased pain at rest. Its main detractors argue that the motor nerve block effect is deleterious to early ambulation and have promoted adductor canal nerve blocks (ACB). Described by Lund et al in 2011, ACB block main femoral pain sensory contributors to the knee (articular branches of obturator nerve, vastus medialis branch and saphenous nerve) but is more distal to most motor branches to the quadriceps allowing near to normal quadriceps strength. Standard ACB block is performed under ultrasound guidance after surgery completion, still in the operating room (OR). Recent literature has shown the anatomic feasibility of intraoperative ACB via blunt suprapatellar dissection in standard medial parapatellar TKA approaches. The study seeks to determine the effectiveness of standard ultrasound guidance ACB compared with intraoperative ACB.

Conditions

• Knee Osteoarthritis
• Total Knee Arthroplasty
• Nerve Block

Interventions

Type	Name	Description
PROCEDURE	Intraoperative Block	One shot adductor canal nerve block with 20ml of bupivacaine 0.25% through surgical incision
PROCEDURE	Ultrasound Block	One shot adductor canal nerve block with 20ml of bupivacaine 0.25% mid-thigh
PROCEDURE	Intraoperative Placebo	One shot adductor canal nerve infusion with 20ml of saline solution through surgical incision
PROCEDURE	Ultrasound Placebo	One shot adductor canal nerve infusion with 20ml of saline solution mid-thigh

Timeline

• Start date: 2018-11-12
• Primary completion: 2022-05-12
• Completion: 2022-10-24
• First posted: 2018-11-07
• Last updated: 2022-10-26

Locations

1 site across 1 country: Chile