Trials / Active Not Recruiting
Active Not RecruitingNCT03712566
Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 39 (actual)
- Sponsor
- University Health Network, Toronto · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is prospective research study which will include patients with recurrent or metastatic squamous cell carcinoma of the head and neck, esophagus and anal canal starting on first-line platinum based chemotherapy or any line of immunotherapy treatment.This study aims to characterize the dynamic changes in genomic, epigenetic, immune profiling and imaging data during treatment with systemic therapy. Patients will have archived tumor samples requested as well as blood samples collected at up to four time points to analyze these changes. Imaging data will be derived from patients' routine CT scans before and after treatment.
Conditions
- Cancer
- Esophagus Squamous Cell Carcinoma
- Squamous Cell Carcinoma of the Head and Neck
- Anal Canal Squamous Cell Carcinoma
- Metastatic Cancer
Timeline
- Start date
- 2018-11-06
- Primary completion
- 2027-01-01
- Completion
- 2027-01-01
- First posted
- 2018-10-19
- Last updated
- 2026-01-08
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT03712566. Inclusion in this directory is not an endorsement.