Clinical Trials Directory

Trials / Completed

CompletedNCT03707106

Benefits of a Cognitive Behavioral Therapy Intervention for Smoking Cessation Supported by Virtual Reality Smoking Cue Exposure

An Efficacy Study Using an Established Cognitive Behavioral Therapy Manual for Smoking Cessation Comparing the Benefit of Virtual Reality Cue Exposure to a Specific Stress Reduction Protocol for Relapse Prevention

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
246 (actual)
Sponsor
University Hospital Tuebingen · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Cognitive-behavioral therapy (CBT) combined with medication is an established intervention for smoking cessation. However, long-term abstinence rates of maximum 35% are yielded. Moreover, acceptance of drug treatment is partly very low. Professional recommendation of drug treatment besides nicotine-replacement aids is restrained considering side effects and contraindications. Currently, cue exposure is highly discussed as intervention for craving reduction supporting CBT. There is evidence for benefits of cue exposure optimizing smoking cessation outcomes, as well as evidence for efficacy of exposure in virtual reality (VR) up to date. However, this is the first randomized controlled study focusing on efficacy increases by VR cue exposure supporting an established CBT smoking cessation manual. The control group receives a specific stress reduction treatment (independent of smoking cues), namely, the Progressive Muscle Relaxation (PMR, according to Jacobson) additionally to the established smoking cessation CBT.

Conditions

Interventions

TypeNameDescription
BEHAVIORALCBT smoking cessationan established protocol for smoking cessation based on cognitive behavioral therapy
BEHAVIORALvirtual reality based cue exposuresmoking cue exposure in virtual reality
BEHAVIORALprogressive muscle relaxationProgressive muscle relaxation for unspecific stress reduction

Timeline

Start date
2017-01-01
Primary completion
2021-07-02
Completion
2021-07-02
First posted
2018-10-16
Last updated
2023-12-05

Locations

2 sites across 1 country: Germany

Source: ClinicalTrials.gov record NCT03707106. Inclusion in this directory is not an endorsement.