Trials / Completed
CompletedNCT03704415
Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 97 (actual)
- Sponsor
- Helsinki University Central Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
This randomized study compares operative techniques in chronic rhinosinusitis with polyposis (CRSwNP) surgery. It aims to evaluate outcomes in asthma and CRSwNP, safety and costs. The investigators want to see if patients with certain clinical and/or genetic predispositions will benefit from extended surgery. They also aim to find biomarkers for detection and management models for of severe airway inflammation and to further develop markers for progressive disease forms.
Detailed description
Please see study protocol
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Extended endoscopic sinus surgery | ESS of all sinuses |
| PROCEDURE | Limited endoscopic sinus surgery | Partial ethmoidectomy |
Timeline
- Start date
- 2018-10-23
- Primary completion
- 2024-10-23
- Completion
- 2024-10-23
- First posted
- 2018-10-12
- Last updated
- 2025-03-18
Locations
3 sites across 2 countries: Finland, Netherlands
Source: ClinicalTrials.gov record NCT03704415. Inclusion in this directory is not an endorsement.