Trials / Completed
CompletedNCT03701932
Mental Activity During (TMS) Therapy for Depression
Mental Activity During Transcranial Magnetic Stimulation (TMS) Therapy for Depression
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 11 (actual)
- Sponsor
- Augusta University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to assess the effects of different types of mental activity performed while receiving transcranial magnetic stimulation (TMS) for the treatment of major depressive disorder. Our primary aim for this study is to assess the feasibility of combining TMS and computer based cognitive exercise in patients with major depressive disorder who may also have some degree of cognitive dysfunction, and to formally measure changes in mood and cognition over the course of the study.
Detailed description
Patients will receive TMS treatment daily for 6 weeks as part of their standard care. They will complete clinical assessments and participate in cognitive retraining through completion of 15 hours of Lumosity gaming cognitive exercises while simultaneously receiving active TMS stimulation. Those participants in the control group will complete 15 hours of computer gaming activity during the administration of active stimulation. Computer games in the control group exercises are elected by the patient from a library of intellectually and motivationally engaging games drawn from several gaming software compilations that includes Play 101 Games and Hoyle Puzzle and Board Games.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | TMS and Lumosity®cognitive retraining | The Lumosity® training includes exercises for speed, memory, attention, flexibility, and problem solving. Subjects will complete this battery while receiving TMS treatment. |
| BEHAVIORAL | TMS and non cognitive computer games | Subjects will play computer games while receiving TMS treatment. |
Timeline
- Start date
- 2015-03-06
- Primary completion
- 2019-07-31
- Completion
- 2019-07-31
- First posted
- 2018-10-10
- Last updated
- 2020-08-28
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03701932. Inclusion in this directory is not an endorsement.