NCT03701633

Uterine Artery Doppler Changes Prior and After Breastfeeding

Postpartum Uterine Artery Doppler Changes Prior and After Breastfeeding

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Rambam Health Care Campus · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

We aim to determine whether there are any differences in the UtA doppler measurements in postpartum women prior and right after breastfeeding.

Detailed description

There is emerging evidence linking abnormal UtA Doppler indices in the postpartum period as a risk factor for developing future cardiovascular disorders. Thus far, no study considered the postpartum physiology itself as a possible confounder. If one wishes to draw conclusions about future cardiovascular risk, the role of oxytocin as a confounder must be determined. In the current study, we aim to determine whether oxytocin, physiologically produced during breastfeeding, has an effect on the UtA Doppler measurements in the postpartum period.

Conditions

• Breastfeeding

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Postpartum ultrasound	Measurements of the UtA doppler ultrasound will be carried out twice for each eligible woman on the second day postpartum. The first measurement will take place just prior to a planned breastfeeding. The second measurement will be followed immediately (within 10 min) after the breastfeeding session.

Timeline

• Start date: 2018-11-01
• Primary completion: 2019-10-01
• Completion: 2020-03-01
• First posted: 2018-10-10
• Last updated: 2018-12-27

Locations

1 site across 1 country: Israel