NCT03692858

IPACK Block in Total Knee Arthroplasty

IPACK Block Efficacy as a Part of Multimodal Analgesia in Total Knee Arthroplasty. A Prospective, Randomized, Controlled, Double Blinded Study

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Asklepieion Voulas General Hospital · Other Government
• Sex: All
• Age: 14 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

100 patients ASA I-III, undergoing total knee arthroplasty under spinal anesthesia, will be randomly assigned into one of two groups, namely group A (n=50), where an adductor canal block and an IPACK block will be performed preoperatively and group B (n=50) where an adductor canal block only will be performed preoperatively. All patients will receive a standardized multimodal approach, including pregabalin, paracetamol, and PCA with morphine. NRS scores in static and dynamic conditions during the first 48 hours postoperatively, morphine consumption during the first 24 hours postoperatively will be measured and additionally, patient satisfaction, complications, range of knee motion, moblization, functionality, delirium ocurence will be recorded. Chronic pain will be assessed in 3 and 6 months postoperatively.

Conditions

• Total Knee Arthroplasty

Interventions

Type	Name	Description
DRUG	Adductor Canal Block plus IPACK Block	Adductor Canal Block plus IPACK Block using Ropivacaine
DRUG	Adductor Canal Block	Adductor Canal Block using Ropivacaine

Timeline

• Start date: 2018-10-01
• Primary completion: 2020-06-01
• Completion: 2020-07-01
• First posted: 2018-10-02
• Last updated: 2019-10-22

Locations

1 site across 1 country: Greece