Clinical Trials Directory

Trials / Completed

CompletedNCT03684590

ANI Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia

A Prospective, Randomized, PACU Blinded Study to Compare ANI-guided Analgesic Administration Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
102 (actual)
Sponsor
University of Texas Southwestern Medical Center · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Accepted

Summary

This study aims to be a randomized, controlled study of ANI-guided opioid administration versus standard clinical practice in surgical patients undergoing general anesthesia with balanced sevoflurane-fentanyl. Patients will be randomly assigned to 2 groups- ANI vs. standard care. The intraoperative and postoperative management of all patients will be standardized by protocol. The PACU nurses and postop assessor will be blinded as to which group the patient is in.

Conditions

Interventions

TypeNameDescription
DEVICEANI-guided opioid administrationIntraoperative opioid will be administered guided by analgesia nociceptive index (ANI) values measured by ANI monitor (MetroDoloris Medical Systems, Lille, France)
OTHERStandard opioid administrationIntraoperative opioid will be administered according to standard practice during surgery.

Timeline

Start date
2019-07-30
Primary completion
2023-03-06
Completion
2023-03-06
First posted
2018-09-25
Last updated
2025-04-30
Results posted
2024-06-12

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03684590. Inclusion in this directory is not an endorsement.