NCT03681314

Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU)

Long-term Outcomes of Umbilical Cord Milking in Term and Late Preterm Neonates Who Are Depressed at Birth

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Nemours Children's Clinic · Academic / Other
• Sex: All
• Age: 3 Months – 26 Months
• Healthy volunteers: Not accepted

Summary

An extension of the MIDAB trial, the MIDAB-Follow-up trial will evaluate the neurodevelopmental outcomes at 22-26 months age of term/late preterm infants who were depressed at birth and received umbilical cord milking (UCM) or immediate cord clamping (ICC).

Detailed description

The MIDAB-Follow-up trial will examine the difference in survival and neurodevelopmental impairment of infants who were depressed at birth and enrolled in MIDAB trial. The difference in survival and neurodevelopmental impairment in infants who received UCM and ICC will be assessed using standardized neurological and developmental assessment tools at 22-26 months of age.

Conditions

• Hypoxic-Ischemic Encephalopathy
• Birth Asphyxia

Interventions

Type	Name	Description
OTHER	Umbilical Cord Milking	At delivery, the umbilical cord is grasped, and blood is pushed toward the infant 4 times before the cord is clamped. This procedure infuses a placental transfusion of blood into the infant and can be done in 10-15 seconds.

Timeline

• Start date: 2022-10-17
• Primary completion: 2024-06-16
• Completion: 2026-08-16
• First posted: 2018-09-24
• Last updated: 2023-04-25

Locations

3 sites across 1 country: India