NCT03668457

A Multi-component Intervention to Improve Medication Adherence in People With Depressive Disorders

Effectiveness and Cost-effectiveness of a Multi-component Intervention to Improve Medication Adherence in People With Depressive Disorders

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 170 (actual)
• Sponsor: Servicio Canario de Salud · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Objective: The study of medication adherence in depression (MAPDep study) aims to evaluate the effectiveness and cost-effectiveness of a multi-component strategy to enhance patient-centered care to improve adherence toward medications in patients with depression, formed by an educational intervention to psychiatrists and/or a collaborative care intervention group to patients and relatives plus a reminder system through the use of a mobile APP. Methods: The objective will be assessed under an open multicenter, clinical controlled trial with random allocation by clusters to one of three interventions or to usual care (control arm). In group 1 only patients and family members receive intervention, in group 2 only psychiatrists receive intervention, and group 3 is a combined intervention for patients and psychiatrists. The main measure will be the change in medication adherence rate. Secondary endpoints are depression, emotional distress, health-related quality of life, physical functioning, patients' knowledge about their medications, provider beliefs regarding patient-centeredness, and healthcare resource utilization.

Conditions

• Depressive Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Intervention to Patients	Multifaceted intervention consisting of: 1. A collaborative care management intervention, including depression education, medication management and behavioral activation. 2. Use of a medication reminder mobile app.
BEHAVIORAL	Intervention to Psychiatrists	Educational intervention consisting of theoretical and practical sessions to to improve communication and negotiation abilities, and to develop skills to promote patient-centered care and shared decision-making.
OTHER	Control	Other: Usual care Usual care for depressive disorder received in mental health units

Timeline

• Start date: 2020-03-01
• Primary completion: 2022-11-01
• Completion: 2022-11-01
• First posted: 2018-09-12
• Last updated: 2023-04-12

Locations

1 site across 1 country: Spain