NCT03661164

Iontophoretic Transepithelial Corneal Cross-linking in Pediatric Patients

Factors Influencing Keratoconus Progression After Iontophoretic Transepithelial Corneal Cross-linking in Pediatric Patients: Three Year Follow up

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 22 (actual)
• Sponsor: Luca Buzzonetti · Academic / Other
• Sex: All
• Age: 8 Years – 18 Years
• Healthy volunteers: —

Summary

To report three year follow up in pediatric patients with keratoconus after iontophoretic transepithelial corneal cross-linking (CXL) to assess preoperative factors that may influence ectasia progression

Detailed description

Purpose: To report three year follow up in pediatric patients with keratoconus after iontophoretic transepithelial corneal cross-linking (CXL) to assess preoperative factors that may influence ectasia progression. Methods: Thirthyfive eyes of 22 consecutive pediatric patients (mean age 14.3±2.5 years) with keratoconus are evaluated in this retrospective study. Subgroup A and B are made up in function of progression in maximum K (Kmax,) defined as steepening of 1.0 diopter or more recorded three year after CXL. Corrected distance visual acuity (CDVA), spherical equivalent, topographic cone location, Kmax, posterior elevation of the thinnest point and thinnest point are evaluated. A paired Student t test is used to compare preoperative and 12, 24, and 36 month postoperative da-ta. A P value \<0.05 was considered significant.

Conditions

• Keratoconus

Interventions

Type	Name	Description
PROCEDURE	corneal cross linking	Iontophoretic corneal cross linking

Timeline

• Start date: 2013-05-01
• Primary completion: 2015-06-30
• Completion: 2015-06-30
• First posted: 2018-09-07
• Last updated: 2018-09-11