Trials / Completed
CompletedNCT03660280
Probiotics to Treat "Inflammatory Depression"
Probiotics to Treat "Inflammatory Depression" - a Randomized Controlled Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 75 (actual)
- Sponsor
- Region Skane · Academic / Other
- Sex
- All
- Age
- 18 Years – 85 Years
- Healthy volunteers
- Not accepted
Summary
The main aims of this project are to test if: i) Specific probiotic lactobacilli (added to stabilized ongoing treatment) are efficacious in treating depressive symptoms in individuals with low-grade inflammation, defined using high sensitivity C-reactive protein (hs-CRP) and BMI. ii) This effect is mediated through decrease of inflammation, estimated by treatment-associated changes in blood and faeces biomarkers. Secondary aims are to investigate the relationship between specific depressive symptoms and inflammation and if there is a correlation between certain pro-inflammatory or metabolic markers and depression.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Probiotics | Specific probiotic lactobacilli (added to stabilized ongoing treatment) |
| OTHER | Placebo | Placebo |
Timeline
- Start date
- 2018-11-06
- Primary completion
- 2023-09-18
- Completion
- 2023-09-18
- First posted
- 2018-09-06
- Last updated
- 2023-11-18
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT03660280. Inclusion in this directory is not an endorsement.