Clinical Trials Directory

Trials / Unknown

UnknownNCT03658850

Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill Patients

Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill Patients: a Randomized Controlled Trial

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
184 (estimated)
Sponsor
University of Sao Paulo · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

HYDRA is a randomized clinical trial designed to evaluate safety and efficiency of hydrochlorothiazide in critical patients with hypernatremia

Conditions

Interventions

TypeNameDescription
DRUGHydrochlorothiazide 50Mgfor the experimental group received a hydrochlorothiazide tablet on presentation of 50mg or equivalent enteral solution every 12h (total of 100mg per day) enterally on day 0 (D0) until day 3
DRUGPlacebosfor the placebo group will receive one tablet or equivalent volume of enteral solution of inert substance, identical to the hydrochlorothiazide presentations, every 12 hours until day 3

Timeline

Start date
2018-10-01
Primary completion
2019-12-10
Completion
2020-03-10
First posted
2018-09-05
Last updated
2019-04-30

Locations

1 site across 1 country: Brazil

Source: ClinicalTrials.gov record NCT03658850. Inclusion in this directory is not an endorsement.