NCT03643913

The Effect of Deep Neuromuscular Block and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Shoulder Surgery Using a Deltopectoral Approach

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Universitaire Ziekenhuizen KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The study evaluates wether deep neuromuscular block during entire surgical procedure to the gleno-humeral joint or the proximal humerus using a deltoideo-pectoral approach results in less muscular damage to the deltoid muscle and therefore less post-operative pain and an earlier functional recovery..

Conditions

• Shoulder Pain
• Anesthesia

Interventions

Type	Name	Description
PROCEDURE	Deep neuromuscular block	Deep neuromuscular block requiring higher doses of Esmeron to target a post tetanic count (PTC) of 1-2 and higher doses of Bridion to reverse the block (4mg/kg).
PROCEDURE	Moderate neuromuscular block	Normal neuromuscular block requiring dosis of Esmeron to target a train of four (TOF) count of max 2 and lower doses of Bridion to reverse the block (2mg/kg).
DRUG	Neuromuscular Blocking Agents and reversing agents	Deep neuromuscular block versus moderate neuromuscular block.

Timeline

• Start date: 2018-12-18
• Primary completion: 2024-11-27
• Completion: 2024-11-27
• First posted: 2018-08-23
• Last updated: 2024-12-12

Locations

1 site across 1 country: Belgium