NCT03594968

Oxidative Stress in Polycystic Ovary Syndrome With Periodontal Disease and Dental Caries Lesions

Polycystic Ovary Syndrome With Periodontal Disease and Dental Caries

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 206 (actual)
• Sponsor: Recep Tayyip Erdogan University Training and Research Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 24 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the oxidative stress parameters in females with polycystic ovary syndrome (PCOS) and clinically healthy. Because of the fact that both oral disease included periodontitis and dental caries, and metabolic syndrome are associated with systemic inflammation, these two disorders may be linked through a common pathophysiologic pathway

Detailed description

Power analysis was performed with the G-Power software package to determine sample size. To cover possible data loss, 10% of a group were added to each group. Medical and dental examination will be performed both of control and experimental groups. Age and body mass index (BMI) will be recorded. In dental examination decayed, missing, or filled teeth (DMFT) index will be used according to World Health Organization (WHO 1997) criteria. All teeth were visually using the International Caries Detection and Assessment System (ICDAS-II). To analyze the correlation between oral health status and polycystic ovary syndrome linear regression test and for comparison of both the groups (case and control), two sample t test and chi square test were used.

Conditions

• Polycystic Ovary Syndrome
• Dental Caries

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	polycystic ovary syndrome	3 to 5th day of the women's normal cycle, we will perform a routine gynecological examination, a basic vaginal ultrasound, a basal hormone profile evaluation

Timeline

• Start date: 2018-04-15
• Primary completion: 2019-03-30
• Completion: 2019-05-15
• First posted: 2018-07-20
• Last updated: 2021-09-09

Locations

1 site across 1 country: Turkey (Türkiye)