NCT03572569

Risk Stratification in Children and Adolescents With Primary Cardiomyopathy

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: German Heart Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

RIKADA is a prospective study performing systematic family screening including clinical and genetic testing in pediatric patients with primary cardiomyopathy and their first-degree relatives with the aim to facilitate risk stratification.

Detailed description

RIKADA is a long-term prospective study performing in-depth phenotype and genotype characterization in children and adolescents with primary cardiomyopathy and their first-degree family members. Family screening contains complete cardiac work-up with medical history, physical examination, 12-lead-/Holter-electrocardiogram, cardiopulmonary exercise testing, echocardiography, cardiovascular magnetic resonance (CMR) and laboratory including genetic testing. The aim is to facilitate early identification of at-risk individuals and contribute to patient-specific follow-up and therapy regimes preventing progressive heart failure and arrhythmia in pediatric CMP.

Conditions

• Primary Cardiomyopathy
• Dilated Cardiomyopathy
• Hypertrophic Cardiomyopathy
• Left Ventricular Noncompaction
• Restrictive Cardiomyopathy
• Arrhythmogenic Right Ventricular Cardiomyopathy

Timeline

• Start date: 2013-01-01
• Primary completion: 2020-12-01
• Completion: 2020-12-01
• First posted: 2018-06-28
• Last updated: 2018-06-28

Locations

2 sites across 1 country: Germany