NCT03554343

Sun May Arise on SMA : Newborn Screening of Spinal Muscular Atrophy in Belgium

Sun May Arise on SMA : Newborn Screening of SMA in Belgium

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 136,339 (actual)
• Sponsor: Centre Hospitalier Régional de la Citadelle · Academic / Other
• Sex: All
• Age: 7 Days
• Healthy volunteers: Not accepted

Summary

Medico-economic study of Newborn screening of Spinal Muscular Atrophy

Detailed description

The aim of this project is to demonstrate the feasibility and the medico-economic impact of a spinal muscular atrophy neonatal screening in a European country. We propose a 3-year-neonatal screening program in Southern Belgium (Wallonia-Brussels Federation) where there is 59.000 newborns/year, among whom 6 are affected by spinal muscular atrophy.

Conditions

• Spinal Muscular Atrophy

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	test for SMN1 exon 7 deletion	Newborns are screened for SMN1 exon 7 deletion through standard NBS practice Positive case are promptly referred to reference centers

Timeline

• Start date: 2018-03-05
• Primary completion: 2021-02-28
• Completion: 2021-02-28
• First posted: 2018-06-13
• Last updated: 2021-03-10

Locations

1 site across 1 country: Belgium