NCT03539432

Exploration of Gemfibrozil as a Treatment for AUD

Exploration of Gemfibrozil as a Treatment for Alcohol Use Disorder

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: The Mind Research Network · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study will examine the efficacy of the medication gemfibrozil in reducing alcohol consumption in individuals with an alcohol use disorder who are seeking treatment for alcohol-related problems. Twenty individuals will be randomized to receive four weeks of either gemfibrozil or placebo and retrospective reports of alcohol use will be collected throughout the trial. In addition, brain imaging measures will be collected at baseline and after two weeks of treatment to determine the effects of gemfibrozil on brain functioning.

Conditions

• Alcohol Use Disorder

Interventions

Type	Name	Description
DRUG	Gemfibrozil 600 MG	Gemfibrozil capsules (600 mg) taken twice per day
DRUG	Placebo oral capsule	Microcrystalline cellulose powder packaged in capsules identical to the experimental medication

Timeline

• Start date: 2018-05-16
• Primary completion: 2018-12-30
• Completion: 2018-12-30
• First posted: 2018-05-29
• Last updated: 2021-10-29
• Results posted: 2021-10-18

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study