NCT03531970

Effect of Lidocaine/Dexamethasone on the Success of IANB

Effect of Lidocaine/Dexamethasone on the Success of IANB in Patients With Irreversible Pulpitis

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Isfahan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this prospective, randomized, double-blind study was to compare the success rate of IAN block injection carried out with two cartridges of 2% lidocaine with 1:80000 epinephrine each combined with 0.2 ml dexamethasone versus two cartridges of 2% lidocaine with 1:80000 epinephrine each combined with 0.2 ml sterile distilled water for endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.

Detailed description

Several investigations have been carried out to demonstrate the effect of dexamethasone added to local anesthetics in regional block injections. These investigations shown that the addition of dexamethasone to local anaesthetics may prolong the duration of anesthesia and also results in a faster onset. It is hypothesized that dexamethasone added to lidocaine may affect the success rate of inferior alveolar nerve block

Conditions

• Local Anesthesia

Interventions

Type	Name	Description
DRUG	2% lidocaine with 1:80,000 epinephrine	Anesthetic solution
DRUG	Dexamethasone	Corticostroide
DRUG	Placebo	Placebo

Timeline

• Start date: 2016-08-01
• Primary completion: 2017-08-01
• Completion: 2017-12-01
• First posted: 2018-05-22
• Last updated: 2018-05-22

Locations

1 site across 1 country: Iran