Trials / Completed
CompletedNCT03519022
Behavioral Effects of Drugs: Inpatient (35)
Influence of Methylphenidate and Duloxetine Maintenance on Pharmacodynamic Effects of Cocaine
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 9 (actual)
- Sponsor
- Craig Rush · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This study will determine the influence of methylphenidate (Metadate®) and duloxetine (Cymbalta®), alone and in combination, on the reinforcing, subjective and physiological effects of cocaine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Cocaine | The pharmacodynamic effects of cocaine will be determined during maintenance on placebo and duloxetine. |
| DRUG | Placebo oral capsule | The pharmacodynamic effects of placebo will be determined during maintenance on placebo and duloxetine. |
| DRUG | Methylphenidate | The pharmacodynamic effects of methylphenidate maintenance will be determined during maintenance on placebo and duloxetine. |
Timeline
- Start date
- 2018-06-01
- Primary completion
- 2019-05-31
- Completion
- 2019-05-31
- First posted
- 2018-05-08
- Last updated
- 2019-06-25
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT03519022. Inclusion in this directory is not an endorsement.