Clinical Trials Directory

Trials / Completed

CompletedNCT03518762

Sustained Lung Inflation in Preterm Infants

Effect of Application of Sustained Lung Inflation on the Respiratory Outcome of Preterm Infants With Respiratory Distress Syndrome

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
160 (actual)
Sponsor
Kasr El Aini Hospital · Academic / Other
Sex
All
Age
1 Minute
Healthy volunteers
Not accepted

Summary

This is a randomized controlled study to investigate the effect of application of sustained lung inflation (SLI) at birth on the respiratory outcome of preterm infants with respiratory distress syndrome.

Detailed description

Enrolled infants (n=160) were randomized before birth into 2 groups (intervention and control group) in a ratio 1:1. Randomization was done through an online randomizer (www.graphpad.com), and sealed envelopes were used to assign the infant to one of the two groups.

Conditions

Interventions

TypeNameDescription
PROCEDURESustained lung inflation (SLI)SLI was given using a peak pressure of 20 cm H₂O sustained for 15 seconds,using a T-piece resuscitator, Neopuff device
PROCEDUREContinuous positive airway pressure (CPAP)CPAP through an appropriate mask using a pressure 5 cm H₂O,using a T-piece resuscitator, Neopuff device.

Timeline

Start date
2014-12-21
Primary completion
2017-01-18
Completion
2017-09-05
First posted
2018-05-08
Last updated
2020-06-09

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT03518762. Inclusion in this directory is not an endorsement.