NCT03515187

Study on Prevention and Treatment of Dry Eye in Patients Using Glaucoma Drops

A Multicenter Randomized Controlled Trial on Prevention and Treatment of Ocular Surface Injury and Meibomian Gland Dysfunction in Patients Using Anti-Glaucoma Eye Drops

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: Shenzhen Hospital of Southern Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

A multicenter randomized controlled trial on prevention and treatment of ocular surface injury and meibomian gland dysfunction in patients using anti-glaucoma eye drops.

Detailed description

1\. To compare the efficacy of drug therapy (sodium hyaluronate + sodium bromide) and combined therapy (combined with meibomian gland massage based on drug therapy) on drug-induced dry eye caused by long-term use of anti glaucoma drugs; 2. To evaluate the efficacy of sodium hyaluronate in the prevention of ocular surface and meibomian gland dysfunction and structural damage in the early stage of patients using anti glaucoma eye drops.

Conditions

• Dry Eye
• MGD-Meibomian Gland Dysfunction

Interventions

Type	Name	Description
DRUG	0.3% sodium hyaluronate ophthalmic solution	one to two drops in eye, four times per day
DRUG	0.1% sodium bromide solution	one to two drops in eye, twice per day
OTHER	Meibomian gland massage	Physiotherapy
OTHER	Placebo	Vehicle

Timeline

• Start date: 2018-06-01
• Primary completion: 2021-04-01
• Completion: 2021-10-01
• First posted: 2018-05-03
• Last updated: 2018-05-03

Locations

1 site across 1 country: China