NCT03502486

The Effects of an Acute Bout of Exercise on Alcohol and Cocaine Craving - an fNIRS Study

The Effects of Acute Bouts of Moderate and Intense Exercise on Alcohol and Cocaine Craving - an fNIRS Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University of Basel · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The study is a crossover randomised controlled trial. Alcohol or cocaine dependent participants will be recruited from inpatient and outpatient psychiatric treatment centres, on the approval of their treating physician. A healthy control group will be recruited using online advertising. All participants will undergo each of three conditions in a randomised order; 1) 20 minutes of cycle ergometry at 50-60% of maximum heart rate; 2) 20 minutes of exercise at 70-80% of maximum heart rate; 3) 20 minutes of quiet reading. Immediately before and after each condition, participants will be asked to complete a computerised Stroop test, watch a film containing substance-related images, and self-report craving levels. During the Stroop test and film viewing, participants' neural activity will be measured via functional near-infrared spectroscopy

Detailed description

The aim of this study is to examine whether, following acute exercise bouts at moderate and high intensities, reduced craving and increased inhibitory control can be observed in alcohol or cocaine dependent individuals. As the focus of this study is the potential of exercise to be integrated into treatment, individuals in treatment for their dependence, who have been abstinent for a short period, will be recruited.

Conditions

• Substance Use Disorders

Interventions

Type	Name	Description
OTHER	Moderate exercise	20 minutes of cycle ergometry at 50-60% of heart rate max
OTHER	Intense exercise	20 minutes of cycle ergometry at 70-80% of heart rate max
OTHER	Reading	20 minutes of seated reading

Timeline

• Start date: 2017-07-05
• Primary completion: 2019-08-01
• Completion: 2020-11-01
• First posted: 2018-04-18
• Last updated: 2018-04-20

Locations

1 site across 1 country: Switzerland