Clinical Trials Directory

Trials / Completed

CompletedNCT03491462

Arimoclomol in Amyotropic Lateral Sclerosis

A Phase 3, Randomised, Placebo-Controlled Trial of Arimoclomol in Amyotropic Lateral Sclerosis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
245 (actual)
Sponsor
ZevraDenmark · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A multicenter, randomized, double-blind, placebo-controlled, parallel group trial to evaluate the efficacy and safety of arimoclomol in amyotropic lateral sclerosis (ALS)

Detailed description

Screening up to 4 weeks Treatment up to 76 weeks

Conditions

Interventions

TypeNameDescription
DRUGArimoclomol2 capsules (2 x 124 mg arimoclomol base; equivalent to 2 x 200 mg arimoclomol citrate) taken 3 times daily
DRUGPlacebo2 matched placebo capsules taken 3 times daily

Timeline

Start date
2018-07-31
Primary completion
2020-12-18
Completion
2020-12-18
First posted
2018-04-09
Last updated
2023-08-24
Results posted
2023-08-24

Locations

29 sites across 12 countries: United States, Belgium, Canada, France, Germany, Italy, Netherlands, Poland, Spain, Sweden, Switzerland, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03491462. Inclusion in this directory is not an endorsement.