NCT03490851

The Effect of a Breakfast Meal Containing Oat β-glucan on Food Intake at a Subsequent Meal in Normal-weight and Overweight Subjects

The Effect of a Breakfast Meal Containing Oat β-glucan on Food Intake at a Subsequent Meal in Normal-weight and Overweight Subjects: A Randomized, Placebo-controlled Cross-over Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: PepsiCo Global R&D · Industry
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The objectives of this study are to determine, in normal-weight and overweight subjects the effect of: Primary: oatmeal containing 4 g oat β-glucan on food intake at a subsequent meal compared to Cream of Rice cereal. Secondary: (i) oatmeal containing 2 g oat β-glucan on food intake at a subsequent meal compared to Cream of Rice cereal; and (ii) oatmeal containing 2g, 4g and 4g low MW oat beta-glucan on subjective appetite ratings, gastric emptying, postprandial responses of glucose, insulin, ghrelin and PYY levels compared to those elicited by Cream of Rice cereal. In addition, the relationship between amount, MW and viscosity of OBG and the primary and secondary objectives will be determined.

Conditions

• Satiety

Interventions

Type	Name	Description
OTHER	Oatmeal + OatWell28CF Int 1	Intervention involves consumption of one cereal in the beginning of each visit of the crossover sequence.
OTHER	Oatmeal + OatWell28CF Int 2	Intervention involves consumption of one cereal in the beginning of each visit of the crossover sequence.
OTHER	Oatmeal + OatWell28CF Int 3	Intervention involves consumption of one cereal in the beginning of each visit of the crossover sequence.
OTHER	Cream of Rice	Intervention involves consumption of one cereal in the beginning of each visit of the crossover sequence.

Timeline

• Start date: 2017-05-07
• Primary completion: 2017-11-28
• Completion: 2017-11-28
• First posted: 2018-04-06
• Last updated: 2019-12-02

Locations

1 site across 1 country: Canada