Clinical Trials Directory

Trials / Completed

CompletedNCT03481348

Pharyngeal Electrical Stimulation in Amyotrophic Lateral Sclerosis

Pharyngeal Electrical Stimulation in Amyotrophic Lateral Sclerosis: A Pilot Study With 20 Patients

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
20 (actual)
Sponsor
University of Ulm · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

During the course of ALS most patients develop swallowing deficits. In this pilot study we investigate if dysphagia in ALS can be improved by Pharyngeal Electrical Stimulation (PES). PES is Communauté Européenne (CE-) certificated and has been approved for treatment of neurological, oropharyngeal dysphagia. During PES, electrical stimuli are applied at the pharynx via a nasogastral tube with the aim of triggering reorganization processes in damaged brain structures. There is evidence of a positive effect of PES in Stroke and Multiple Sclerosis patients.

Conditions

Interventions

TypeNameDescription
DEVICEPharyngeal Electrical StimulationPharyngeal Electrical Stimulation is applied at the pharynx via a nasogastral tube for 10 minutes per day on 3 consecutive days.

Timeline

Start date
2018-02-01
Primary completion
2020-07-21
Completion
2020-07-21
First posted
2018-03-29
Last updated
2021-03-08

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT03481348. Inclusion in this directory is not an endorsement.