NCT03469037

Effects on Experimental Dyspnea of High Flow Nasal Cannula

Effects on an Experimental Dyspnea by Thoraco-abdominal Elastic Strapping of the High Flow Nasal Cannula

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To develop an experimental model of dyspnea by external thoraco-abdominal elastic strapping at rest in order to study the mechanisms involved in the relief of dyspnea by the administration of high flow by nasal cannula (HFNC).

Detailed description

This study will measure the effect of HFNC on an experimental model of dyspnea induced by thoraco-abdominal elastic strapping on healthy subjects at rest. The study will also compare the effects on dyspnea of the administration of high flow nasal cannula with and without oxygen added.

Conditions

• Dyspnea
• Healthy Volunteers

Interventions

Type	Name	Description
DEVICE	Optiflow with an inspired fraction of oxygen of 100%	Respiratory gaz heated and humidified system of delivery with a fraction of oxygen inspired of 100%
DEVICE	Optiflow with an inspired fraction of oxygen of 21%	Respiratory gaz heated and humidified system of delivery with a fraction of oxygen inspired of 21%

Timeline

• Start date: 2018-05-22
• Primary completion: 2018-11-02
• Completion: 2018-11-02
• First posted: 2018-03-19
• Last updated: 2019-02-15

Locations

2 sites across 1 country: France