NCT03457116

Narcotics vs NSAIDs for Post-operative Analgesia in Outpatient Rhinoplasty

Narcotics vs Non-steroidal Ant Inflammatory Drugs Post-operative Analgesia in Outpatient Rhinoplasty

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: NYU Langone Health · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the efficacy and safety of oral opiate pain medication vs non-steroidal ant inflammatory drugs (NSAIDs) in the treatment of postoperative rhinoplasty pain. This study will also evaluate potential contributing factors affecting the efficacy of these pain control methods. Patients will be randomized to receive either NSAIDs in the form of 400mg of Ibuprofen or Norco (hydrocodone 5mg- acetaminophen 325mg) to be used for post-operative pain. The study will then compare which is more effective in controlling post operative pain.

Conditions

• Rhinoplasty
• Non-steroidal Ant Inflammatory Drugs
• Opioid Use

Interventions

Type	Name	Description
DRUG	Norco	20 tablets of Hydrocodone 5mg-Acetaminophen 325mg (Norco)
DRUG	NSAID	Ibuprofen 400mg for post-operative pain

Timeline

• Start date: 2018-01-30
• Primary completion: 2020-11-02
• Completion: 2020-11-02
• First posted: 2018-03-07
• Last updated: 2021-11-23
• Results posted: 2021-11-23

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study