NCT03445585

Biobank for Cholestatic Liver Diseases.

A Resource of Blood and Other Biospecimens of Patients With Cholestatic Liver Disease and Unaffected Individuals

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 9,150 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

This study is a biobank of specimens and clinical data for use in current and future research to better understand the cholestatic liver diseases primary biliary cirrhosis/cholangitis (PBC) and primary sclerosing cholangitis (PSC).

Detailed description

This study is a biobank of specimens and clinical data for use in current and future research to better understand the cholestatic liver diseases primary biliary cirrhosis/cholangitis (PBC) and primary sclerosing cholangitis (PSC). Blood, saliva, stool, and urine samples will be collected periodically during patient visits, mail-home kit (collected locally), or via remote phlebotomy at a place directed by the subject. Bile and bile duct cells will be collected during clinically necessary Endoscopic Retrograde Cholangiopancreatography (ERCP) procedures being performed at Mayo Clinic for clinical reasons. Anticipated research will focus on multi-omics assessments of biospecimens to better define how these diseases start and progress in order to develop novel tests for early detection of complication and better disease prognostication.

Conditions

• Primary Sclerosing Cholangitis
• Primary Biliary Cirrhosis
• Cholangiocarcinoma
• Liver Cancer

Timeline

• Start date: 2017-01-01
• Primary completion: 2050-01-01
• Completion: 2050-01-01
• First posted: 2018-02-26
• Last updated: 2026-02-17

Locations

1 site across 1 country: United States