NCT03444363

Periodontal Treatment With Diode Laser in the Patients With Diabetes Melitus

Evaluation of Long-Term Effects of Diode Laser Application on Periodontal Healing, Serum C-Reactive Protein and HbA1c Levels in Periodontal Treatment of Uncontrolled Type-2 Diabetic Subjects With Chronic Periodontitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Çanakkale Onsekiz Mart University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

This study aimed to investigate the effects of diode laser (DL) in addition to non-surgical periodontal treatment on periodontal parameters, systemic inflammatory response, and serum hemoglobin A1c (HbA1c) level in patients with uncontrolled type 2 diabetes mellitus (T2DM) and chronic periodontitis.

Detailed description

This study was designed as a randomized, controlled, full-mouth, 6-month clinical trial. 37 patients (20 women and 17 men) with uncontrolled T2DM and chronic periodontitis who were selected from among those admitting to Dentistry Faculty of Inonu University and Turgut Ozal Medical Center completed this study. The patients were divided into two groups. The individuals in the control group underwent placebo laser treatment in addition to scaling and root planing (SRP). The individuals in the study group underwent DL (1 W power) in addition to SRP. Clinical index measurements were performed before treatment (T0), 3 months after treatment (T1), and 6 months after treatment (T2). Plaque index (PI), gingival index (GI), bleeding on probing (BOP), clinical attachment level (CAL), and probing depth (PD) were measured to determine periodontal status. HbA1c and C-reactive protein (CRP) levels were also analyzed using blood samples.

Conditions

• Diabetes Mellitus
• Periodontal Disease

Interventions

Type	Name	Description
DEVICE	Laser group	Laser application in addition to SRP
DEVICE	Control group	Placebo laser application in addition to SRP

Timeline

• Start date: 2013-09-20
• Primary completion: 2014-02-15
• Completion: 2014-12-23
• First posted: 2018-02-23
• Last updated: 2018-02-23

Locations

1 site across 1 country: Turkey (Türkiye)