Trials / Completed
CompletedNCT03429049
A Phase 3 Efficacy and Safety Study of Intra-articular CNTX-4975-05 (Capsaicin) vs Placebo in Subjects With OA Knee Pain
A Randomized, Double-blind, Placebo-controlled, Single Injection, 52-Week Study to Evaluate the Efficacy and Safety of an Intra-articular Injection of CNTX-4975-05 in Subjects With Chronic, Moderate-to-severe Osteoarthritis Knee Pain
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 332 (actual)
- Sponsor
- Centrexion Therapeutics · Industry
- Sex
- All
- Age
- 40 Years – 95 Years
- Healthy volunteers
- Not accepted
Summary
This is a phase 3, randomized, double-blind, placebo-controlled, single injection, 52-week study to evaluate the analgesic efficacy and safety of a single intra-articular (IA) CNTX-4975-05 (capsaicin), compared to IA placebo, in subjects with chronic, moderate-to-severe osteoarthritis (OA) knee pain.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | CNTX-4975-05 | Receiving CNTX-4975-05 injection |
| DRUG | Placebo | Receiving Placebo injection |
Timeline
- Start date
- 2018-01-24
- Primary completion
- 2019-11-22
- Completion
- 2019-11-22
- First posted
- 2018-02-12
- Last updated
- 2022-07-26
- Results posted
- 2022-04-08
Locations
33 sites across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT03429049. Inclusion in this directory is not an endorsement.