NCT03423888

High-flow Nasal Oxygen in Palliative Care: Pilot Study

Acceptability of High-flow Nasal Oxygen to Relieve Dyspnea in Palliative Care: Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In palliative care, the relief of the dyspnea is necessary. Medications for the reduction of dyspnea have side effects. High-flow nasal cannula oxygen therapy (HFNC) is a new way to deliver oxygen. Investigators hypothesize that HNFC is an acceptable technic for the patient with dyspnea in palliative care. A pilot study with 30 patients will be conducted. Acceptability of HNFC will be studied by the time of use by patients of the HNFC during one week. The effectiveness of HNFC in relieving dyspnea will be studied using Borg scale.

Detailed description

Pilot study for acceptability of high flow nasal cannula oxygen therapy in palliative care Population: 30 patients in palliative care (for lung cancer, terminal respiratory failure) who suffer from dyspnea and have oxygen therapy. Patients with curative care are excluded and patients who require non invasive ventilation. An oral consent is asked. Primary objective: acceptability of HNFC in patients with dyspnea in palliative care during one week Secondary objectives: * Tolerance of HNFC at short term (1h and 24h) and long term (7 days) after initiation of HNFC * Efficiency of HNFC at short term Primary outcome: duration of use of the HNFC during 7 days Secondary outcome: * Tolerance: noise of the system of HNFC, side effects of high flow (nasal dryness..) * Efficiency: evaluation of dyspnea by Borg scale and measure of respiratory rate and saturation of oxygen one hour after initiation of HNFC

Conditions

• Dyspnea

Interventions

Type	Name	Description
DEVICE	high-flow nasal cannula oxygen therapy (HNFC)	Set up of high-flow nasal oxygen for patient with dyspnea for a respiratory disease without possibility of curative care. Patients who require a treatment by oxygen are included. After 7 days of treatment, acceptability is evaluated by the duration of use of HNFC.

Timeline

• Start date: 2018-02-13
• Primary completion: 2022-01-25
• Completion: 2022-01-25
• First posted: 2018-02-06
• Last updated: 2022-04-14

Locations

1 site across 1 country: France