NCT03419689

Study Looking at Biomarkers in Ovarian Cancer

Biomarker Discovery Project in High Grade Serous Ovarian Cancer

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 510 (estimated)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a sample study that will collect biological samples (blood, tumor tissue, ascites, and/or other fluids) from gynecological cancer patients for biomarker research. In addition, the results of the testing done on the samples will be given to the participant's treating physician who may use the information to guide treatment decisions.

Conditions

• Gynecologic Cancer

Interventions

Type	Name	Description
PROCEDURE	Tumour tissue collection	Tumour tissue will be taken from samples already removed from surgery or biopsy or by new tumour biopsies: * At the time of diagnosis or progression * Any surgical procedures for management of tumour related medical conditions * At each subsequent relapse or disease progression
PROCEDURE	Blood sample collection	Blood samples will be taken: * At the time of first diagnosis * About 1 week after starting any treatment * At each radiological response assessment * At each subsequent relapse or disease progression
PROCEDURE	Ascites Collection	Ascites will be collected if paracentesis is required during any of the following time points: * At the time of diagnosis or progression * Any surgical procedures for management of tumour related medical conditions * At each subsequent relapse or disease progression
PROCEDURE	Fluid Collection	Additional fluid will be collected at any time a procedure for clinical management that involves the drainage of fluid (i.e. thoracentesis, or drainage of cystic lesion) is required.

Timeline

• Start date: 2018-01-08
• Primary completion: 2028-06-08
• Completion: 2028-06-08
• First posted: 2018-02-05
• Last updated: 2025-12-04

Locations

7 sites across 1 country: Canada