NCT03403166

Metabolomics of the Dietary Approaches to Stop Hypertension (DASH) Dietary Pattern

Metabolomics of the Dietary Approaches to Stop Hypertension (DASH) Dietary Pattern: A Secondary Data Analysis of the DASH Trial

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 459 (actual)
• Sponsor: Johns Hopkins Bloomberg School of Public Health · Academic / Other
• Sex: All
• Age: 22 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The present record represents a secondary data analysis of the Dietary Approaches to Stop Hypertension (DASH) trial. Study data and specimens were accessed through the National Heart, Lung, and Blood Institute (NHLBI) Biologic Specimen and Data Repository Coordinating Center (BioLINCC). A global, untargeted, metabolomic profile was used to investigate biomarkers of the DASH dietary pattern as well as blood pressure change.

Detailed description

The present study was conducted in order to: 1) quantify the metabolomic expression of the DASH dietary pattern; and 2) examine the relationship between metabolites that reflect the DASH dietary pattern and blood pressure change. This secondary data analysis leverages the completed DASH trial, a randomized feeding trial (N=459).

Conditions

• Dietary Modification
• Blood Pressure

Interventions

Type	Name	Description
BEHAVIORAL	DASH diet	Diet intervention
BEHAVIORAL	Fruits and vegetables diet	Diet intervention
BEHAVIORAL	Control diet	Diet intervention

Timeline

• Start date: 1993-08-01
• Primary completion: 1997-07-01
• Completion: 2017-06-01
• First posted: 2018-01-18
• Last updated: 2018-01-18