NCT03385850

The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis

The Roles of Th17/Treg Cells and IL-23/IL-17 Axis in the Mechanisms of Early Enteral Nutrition Improving Immune Function of Sepsis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 53 (actual)
• Sponsor: Nanjing First Hospital, Nanjing Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The investigators aim to evaluate the roles of Th17/Treg cells and IL-23/IL-17 axis in the mechanisms of early enteral nutrition (EEN) correcting immune imbalance of sepsis by means of improving the intestinal flora disturbance. The results of this study would lay the foundation for revealing the mechanisms of EEN improving immune imbalance of sepsis and provide a new idea to the early treatment of sepsis

Conditions

• Sepsis
• Immune System Disorder
• Enteral Feeding

Interventions

Type	Name	Description
OTHER	enteral nutrition	early enteral nutrition group or delayed enteral nutrition group

Timeline

• Start date: 2017-10-01
• Primary completion: 2018-06-30
• Completion: 2018-12-31
• First posted: 2017-12-29
• Last updated: 2019-03-05

Locations

1 site across 1 country: China