NCT03372382

Ibuprofen and Acetaminophen Versus Ibuprofen and Acetaminophen Plus Hydrocodone for Analgesia After Cesarean Section

Ibuprofen and Acetaminophen Versus Ibuprofen and Acetaminophen Plus Hydrocodone for Analgesia After Cesarean Section: A Prospective, Randomized Control Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 170 (actual)
• Sponsor: The University of Texas Health Science Center, Houston · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Postpartum patients delivered by cesarean section will be randomized to NSAIDS Vs NSAIDS plus opioid

Detailed description

Women will be approached priors to discharge from the hospital, if they meet inclusion criteria and consent for the study, they will be randomized to one of two possible analgesic regimens. They will be followed at 1-2 weeks and 4-6 weeks after discharge to assess pain level.

Conditions

• Opioid Use
• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	Ibuprofen	NSAID
DRUG	Acetaminophen	analgesic
DRUG	Norco	acetaminophen plus opioid

Timeline

• Start date: 2017-12-13
• Primary completion: 2018-04-10
• Completion: 2018-04-10
• First posted: 2017-12-13
• Last updated: 2019-07-02
• Results posted: 2019-07-02

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study