NCT03358641

The Relationship Between Physical Activity and Radiographic Osteoarthritis Worsening

The Relationship Between Physical Activity and Radiographic Osteoarthritis Worsening: Wuchuan Osteoarthritis Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,200 (estimated)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: —

Summary

Wuchuan Osteoarthritis Study is a population-based longitudinal study of natural history of knee osteoarthritis and its risk factors. At baseline and follow-up visits, IPA-Q questionnaire and a radiographs at tibiofemoral (TF) joints will be taken in order to assess the relationship between physical activity and radiographic osteoarthritis worsening.

Detailed description

1025 residents aged ≥ 50 years will be recruited using door-to-door enumeration in randomly selected rural communities in Wuchuan, China, and will be followed in 3 years. At baseline and follow-up visits, subjects will complete a home interview (including, but not limited to, socio-demographic factors, physical activity level using IPA-Q questionnaire,WOMAC questionnaire) and have a weight-bearing posteroanterior semiflexed view of radiographs at tibiofemoral (TF) joints. Radiographic osteoarthritis (ROA) worsening for a knee is defined if its Kellgren and Lawrence (K/L) grade increases by at least 1 grade except for the change from 0 to 1 during follow-up. The relationship between level of physical activity and ROA worsening will be assessed.

Conditions

• Osteoarthritis, Knee

Interventions

Type	Name	Description
OTHER	level of physical activity	According to the result of IPA-Q questionnaire, participants are divided in three groups: low level, moderate level, high level of physical activity.

Timeline

• Start date: 2018-01-01
• Primary completion: 2020-12-31
• Completion: 2020-12-31
• First posted: 2017-11-30
• Last updated: 2017-11-30