NCT03354546

Development and Validation of a Preoperative Frailty Index Using Health Administrative Data

Creation, Evaluation and Validation of a Preoperative Frailty Index Using Health Administrative Data: a Population-based Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 511,285 (actual)
• Sponsor: Ottawa Hospital Research Institute · Academic / Other
• Sex: All
• Age: 66 Years
• Healthy volunteers: Not accepted

Summary

The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.

Detailed description

The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices. Once derived the index will be tested to measure its association with outcomes, as well as its discrimination. Various representations of the frailty index will be tested (primary-as a continuous measure; secondary as a binary, categorical and fractional polynomial variable). Performance in subgroups will also be evaluated,

Conditions

• Frail Elderly Syndrome
• Surgery
• Outcomes
• Predictive Value of Tests

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Frailty index	A frailty index composed of variables from health administrative data that cover multi-system health issues. Deficits will be coded as present or absent, and the number of deficits present will be divided by the total number of deficits present to provide an overall score between 0-1.

Timeline

• Start date: 2002-04-01
• Primary completion: 2016-03-31
• Completion: 2016-03-31
• First posted: 2017-11-28
• Last updated: 2024-09-23
• Results posted: 2024-09-23