NCT03353337

A Study of Aerobic Exercise for Patients With Bipolar Disorder

A Randomised Controlled Trial of Aerobic Exercise for Inpatients With Bipolar Affective Disorder

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 210 (estimated)
• Sponsor: Guangzhou Psychiatric Hospital · Other Government
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study will investigate the effects of aerobic exercise on mental states, cognition, BDNF, and long-term outcomes in patients with bipolar disorder.

Detailed description

Multiple cognitive impairments are common in patients with bipolar disorder. Preliminary evidence shows that aerobic exercise might have positive effects in enhancing cognition and improving clinical symptoms in patients with mood disorders. This randomized controlled trial will investigate short-term (1 months) effects of aerobic exercise on cognition and clinical symptoms as well as the long-term (12 months) effects on decreasing the recurrence rate.

Conditions

• Bipolar Disorder
• Cognitive Symptom

Interventions

Type	Name	Description
BEHAVIORAL	aerobic exercise	Cycling at the intensity of 50%-70% of maximum heart rate (220-age) for 30 mins per day, 4 days per week, last for 1 months.
BEHAVIORAL	Placebo controlled group	General intensity activities of recreation therapy, including Handicraft manufacture, reading activity, singing entertainment, walking.

Timeline

• Start date: 2017-12-01
• Primary completion: 2019-07-31
• Completion: 2019-12-31
• First posted: 2017-11-27
• Last updated: 2017-11-27

Locations

1 site across 1 country: China