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UnknownNCT03351179

Predictors and Outcomes of In-hospital HFpEF in AMI Patients

Predictors and Outcomes of Hospitalized Heart Failure With Preserved Ejection Fraction Among Patients With First Acute Myocardial Infarction After Reperfusion Treatments

Status
Unknown
Phase
Study type
Observational
Enrollment
500 (estimated)
Sponsor
Xiangjun Yang · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This retrospective observation is to investigate the incidence,clinical outcomes and prognosis of hospitalized heart failure with preserved ejection fraction (HFpEF) in patients with acute myocardial infarction(AMI).

Detailed description

1. Patients with first AMI undergoing primary percutaneous coronary intervention (PCI) in our hospital since January 2013 were retrospectively evaluated. The enrolled subjects were divided into two groups (AMI patients with HFpEF and AMI patients without HF). 2. The investigator collected the clinical data of participants' demographics (age, sex), previous history,risk factors for AMI (hypertension, hyperlipidemia, diabetes mellitus, smoking and stroke), laboratory biomarkers, echocardiographic measurements, clinical characteristics,medical procedures and treatments, as well as in-hospital complications. 3. Two sub-investigators independently analyzed these data by using SPSS software.

Conditions

Interventions

TypeNameDescription
COMBINATION_PRODUCTclinical characteristics, previous history, laboratory bio-markers, echocardiographic measurements, angiographic findings,clinical outcomesThe differences of data(clinical characteristics, history, laboratory biomarkers, echocardiographic measurements, angiographic characteristics and clinical outcomes) in two groups were conducted. The differences between two groups were compared (clinical characteristics, history, laboratory biomarkers, echocardiographic measurements, angiographic characteristics and clinical outcomes) in two groups were compared, and then found the risk factors. Following,the incidence of clinical outcomes and mortality were compared. Then, univariate logistic regression and multivariate logistic regression analysis adjusted for significant risk factors were performed to find out the independent predictive factors. Finally, the ROC was constructed, and the area was evaluated to assess the predicted probability of regression model.

Timeline

Start date
2013-01-01
Primary completion
2018-12-30
Completion
2018-12-30
First posted
2017-11-22
Last updated
2019-01-02

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT03351179. Inclusion in this directory is not an endorsement.