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Trials / Terminated

TerminatedNCT03331939

Effect of Short-term Theta Frequency Stimulation of the Vagus Nerve on Cognition in Patients With Refractory Epilepsy

Effect of Short-term Theta Frequency Stimulation of the Vagus Nerve on Cognition : a Pilot Study

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
2 (actual)
Sponsor
University of California, Davis · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this investigation is data pilot study of the effect of theta frequency stimulation of the vagus nerve on cognitive performance in patients with refractory epilepsy. We will compare the effects of no stimulation, theta frequency (5 Hz), and 'standard' beta frequency stimulation (25-30 Hz) on cognitive measures. We hypothesize that theta frequency VNS will have a positive effect on memory retention. The goal of this study to provide initial data to inform the design of a larger clinical trial to examine the efficacy of theta VNS.

Conditions

Interventions

TypeNameDescription
OTHERno stimulationVagal nerve stimulator will be set to no stimulation
OTHERbeta (25-30 Hz)Vagal nerve stimulator will be set to beta (25-30 Hz)
OTHERTheta (5 Hz)Vagal nerve stimulator will be set to beta (5 Hz)

Timeline

Start date
2017-01-06
Primary completion
2017-10-31
Completion
2017-10-31
First posted
2017-11-06
Last updated
2017-11-06

Source: ClinicalTrials.gov record NCT03331939. Inclusion in this directory is not an endorsement.

Effect of Short-term Theta Frequency Stimulation of the Vagus Nerve on Cognition in Patients With Refractory Epilepsy (NCT03331939) · Clinical Trials Directory