Trials / Completed
CompletedNCT03321487
Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis
Safety and Feasibility of Primary Motor Cortex Blood-Brain Barrier Opening Using Transcranial MR-Guided Focused Ultrasound With Intravenous Ultrasound Contrast Agent in Patients With Amyotrophic Lateral Sclerosis
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 4 (actual)
- Sponsor
- InSightec · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate the safety, tolerability, and feasibility of Blood-Brain Barrier (BBB) opening using transcranial MRI-guided focused ultrasound in conjunction with an intravenous ultrasound contrast agent in patients with Amyotrophic Lateral Sclerosis (ALS).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Blood-Brain Barrier opening with MRgFUS | ExAblate Transcranial MR-guided Focused Ultrasound to temporarily open the Blood-Brain Barrier |
Timeline
- Start date
- 2018-04-13
- Primary completion
- 2021-12-30
- Completion
- 2023-09-11
- First posted
- 2017-10-25
- Last updated
- 2026-03-20
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT03321487. Inclusion in this directory is not an endorsement.