NCT03313024

Berlin-Brandenburg Pregnancy Cohort

Characterization of Immune Cell-trophoblast-interaction in Pregnancy Disorders

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,580 (estimated)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.

Conditions

• Preeclampsia
• Pregnancy Complications
• Diabetes Mellitus in Pregnancy

Timeline

• Start date: 2017-09-26
• Primary completion: 2027-10-01
• Completion: 2027-10-01
• First posted: 2017-10-18
• Last updated: 2018-08-14

Locations

1 site across 1 country: Germany