NCT03308461

Fecal Microbiota Transplantation for Constipation

Fecal Microbiota Transplantation for Constipation With Difficult Defecation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: The Second Hospital of Nanjing Medical University · Academic / Other
• Sex: All
• Age: 14 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Difficult defecation is a common symptom involving with patients'life quality. The stool pattern of these patients might be related to the contribution of gut microbiota. This pilot study proposed hypothesis that stool pattern could be used as a simple index to screen the potential candidates of fecal microbiota transplantation in patients with difficult defecation.

Detailed description

Difficult defecation is a common symptom involving with patients'life quality. The stool pattern of these patients might be related to the contribution of gut microbiota. This pilot study proposed hypothesis that stool pattern could be used as a simple index to screen the potential candidates of fecal microbiota transplantation in patients with difficult defecation. Patients underwent single FMT in this study were divided into hard-stool group and loose-stool group. All patients were assessed before FMT and during 12-week follow-up after FMT.

Conditions

• Gut Microbiota
• Constipation

Interventions

Type	Name	Description
DRUG	Fecal Microbiota suspension	The prepared microbiota suspension was infused into mid-gut.

Timeline

• Start date: 2013-05-01
• Primary completion: 2017-05-01
• Completion: 2017-05-01
• First posted: 2017-10-12
• Last updated: 2017-10-12

Locations

1 site across 1 country: China