NCT03301402

Air Purifier to Improve Endothelial Function and Carotid Intima Thickness

A Randomized Controlled Trial of Air Purifier to Improve Endothelial Function and Carotid Intima Thickness in Older Diabetic People With Cognitive Impairment

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: 70 Years
• Healthy volunteers: Not accepted

Summary

Background: There is epidemiological evidence or link ambient air pollution exposure to the incidence of dementia. Aims or hypotheses: It is hypothesized that reduction in indoor pollutants from air purification improves endothelial function and carotid intima thickness in older diabetic people with cognitive impairment. Subjects and method: People with clinically diagnosis mild cognitive impairment or early dementia will be recruited. After obtaining written consent, the subjects will be assessed cognitive function and arterial health. After baseline measurements, the subjects are randomly assigned to have either filter or no filter installed in the air purifier. The air purifier will be placed in living room of the household of the subject for one year. At one year, the measurements will be repeated. Statistical analysis: Intention to treat analysis will be adopted.

Conditions

• Endothelial Function
• Cognitive Impairment

Interventions

Type	Name	Description
DEVICE	Air purifier	Air purifier with filter at automatic mode on all time

Timeline

• Start date: 2017-09-22
• Primary completion: 2021-01-05
• Completion: 2021-01-05
• First posted: 2017-10-04
• Last updated: 2021-06-01

Locations

1 site across 1 country: Hong Kong