NCT03301285

Efficacy of Zoledronic Acid in Osteoporosis of Children With Multiple Disabilities

Study of Efficacy of Zoledronic Acid in the Management of Osteoporosis in Children With Multiple Disabilities

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main purpose of this study is the evaluation of the efficacy of zoledronic acid on bone density in children with osteoporosis caused by multiple disabilities. Secondary purposes are: 1. Description of child population with osteoporosis in the context of motor impairment in Lorraine region 2. Description of osteoporosis stage (level of bone mineralization and clinical consequences) in children with multiple disabilities 3. Description of current osteoporosis preventive care 4. Description of risk factors associated to bone status (drugs) 5. Evaluation of zoledronic acid treatment on fracture numbers 6. Evaluation of zoledronic acid on phosphocalcic profile 7. Description of side effects of zoledronic acid in this indication 8. Description of treatment effects in the sub-population of children with Rett syndrome.

Conditions

• Multiple Disability
• Osteoporosis

Interventions

Type	Name	Description
DRUG	Zoledronic Acid	Treatment of osteoporosis

Timeline

• Start date: 2017-01-01
• Primary completion: 2017-03-31
• Completion: 2017-03-31
• First posted: 2017-10-04
• Last updated: 2017-10-04

Locations

1 site across 1 country: France