NCT03300778

A Study of Aerobic Exercise for Adolescents With Subthreshold Mood Syndromes

A Randomised Controlled Trial of Aerobic Exercise for Adolescents With Subthreshold Depressive and/or Hypomanic Syndrome and for Non-clinical Adolescents

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 224 (actual)
• Sponsor: Guangzhou Psychiatric Hospital · Other Government
• Sex: All
• Age: 12 Years – 14 Years
• Healthy volunteers: Accepted

Summary

This study will investigate the effects of aerobic exercise on mental states, cognition, and long-term outcomes in adolescents with subthreshold depressive and/or hypomanic syndromes and in non-clinical school children

Detailed description

Subthreshold depressive and hypomanic symptoms are common in adolescents, increasing the risk of developping into depression or bipolar disorder. Preliminary evidence shows that aerobic exercise might have positive effects in enhancing cognition and improving clinical symptoms in non-clinical and preclinical population and patients with mood disorders. This randomized controlled trial will investigate short-term (3 months) effects of aerobic exercise on cognition and clinical symptoms as well as the long-term (18 months) effects on the clinical outcomes of high-risk states.

Conditions

• Depressive Symptoms
• Hypomania Nos Single Episode or Unspecified

Interventions

Type	Name	Description
BEHAVIORAL	aerobic exercise	Running at the intensity of 50%-70% of maximum heart rate (220-age) for 30 mins per day, 4 days per week, last for 3 months
BEHAVIORAL	Placebo controlled group	6 sections of group activities: 3 sections of general psychological education; one section of group game, one section of group poetry reading activity, group singing entertainment.

Timeline

• Start date: 2017-10-10
• Primary completion: 2018-01-05
• Completion: 2018-01-12
• First posted: 2017-10-03
• Last updated: 2018-08-23

Locations

1 site across 1 country: China