NCT03299764

Evaluation of Non-invasive Pursed-lip Breathing Ventilation (PLBV) in Advanced COPD

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 270 (estimated)
• Sponsor: Research Center Borstel · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

Comparison of a conventional non-invasive ventilation to a non-invasive pursed-lip breathing ventilation (PLBV) ventilation in advanced COPD

Detailed description

Intervention: Non-invasive ventilation with dynamic positive pressure during expiration (pursed-lip breathing ventilation, PLBV) Control Conventional bi-level non-invasive ventilation (NIV) with static positive pressures Duration of intervention per patient 3 months as randomized (1:1) followed by 9 months as chosen by patient

Conditions

• COPD

Interventions

Type	Name	Description
DEVICE	Pursed lip breathing ventilation	A non-invasive ventilation device mimicking the pursed lip breathing in COPD patients will be used.
DEVICE	Standard non-invasive ventilation	Standard non-invasive ventilation

Timeline

• Start date: 2017-11-01
• Primary completion: 2026-11-01
• Completion: 2027-07-01
• First posted: 2017-10-03
• Last updated: 2024-04-12

Locations

5 sites across 1 country: Germany