Clinical Trials Directory

Trials / Completed

CompletedNCT03287921

Diagnostic and Therapeutic Approaches to Hyperinflation and Small Airway Disease in COPD

Status
Completed
Phase
Study type
Observational
Enrollment
26 (actual)
Sponsor
Universitätsmedizin Mannheim · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. Hyperinflation and affection of the small airways are two components that are not represented in current diagnostic concepts and may relate to early stages of the disease. Moreover, optimal therapeutic interventions in patients with these distinct features remain unclear. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and initiating therapeutic strategies in early stage COPD within the GOLD recommendations.

Conditions

Interventions

TypeNameDescription
DRUGmono bronchodilatationwithin indication according to current GOLD recommendation
DRUGdual bronchodilatationwithin indication according to current GOLD recommendation

Timeline

Start date
2017-10-02
Primary completion
2018-11-30
Completion
2019-04-11
First posted
2017-09-19
Last updated
2020-03-31

Locations

1 site across 1 country: Germany

Regulatory

Source: ClinicalTrials.gov record NCT03287921. Inclusion in this directory is not an endorsement.

Diagnostic and Therapeutic Approaches to Hyperinflation and Small Airway Disease in COPD (NCT03287921) · Clinical Trials Directory