NCT03268473

Effect of Non-surgical Periodontal Treatment on Oxidative Stress and Antioxidant Status in OSAS

Effect of Non-surgical Periodontal Treatment on Oxidative Stress and Antioxidant Status in Obstructive Sleep Apnea Syndrome (OSAS)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Bezmialem Vakif University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main objective of this study is to compare the effect of the non-surgical periodontal treatment on serum and saliva oxidative stress parameters in patients with periodontitis and obstructive sleep apnea syndrome (OSAS) and in patients with periodontitis only.

Detailed description

There is evidence supporting that OSAS is an independent risk factor for cardiovascular and cerebrovascular diseases such as hypertension, congestive heart failure, myocardial infarction, cardiac-arrhythmia, and stroke.Gender, age, smoking, obesity and diabetes, which are risk factors for periodontitis,It is also common in OSAS at the same time.In addition to common risk factors, both OSAS and periodontitis have been shown to be associated with increased oxidative stress markers. The investigators aimed to investigate whether non-surgical periodontal treatment on serum and saliva oxidative stress parameters in patients with periodontitis and obstructive sleep apnea syndrome (OSAS) and in patients with periodontitis only.

Conditions

• Periodontitis
• Obstructive Sleep Apnea
• OSAS

Interventions

Type	Name	Description
OTHER	Experimental	Experimental: Non-surgical periodontal therapy in patient with OSAS and Periodontitis
OTHER	Control	Control: Non-surgical periodontal therapy in Periodontitis

Timeline

• Start date: 2017-07-01
• Primary completion: 2023-08-01
• Completion: 2023-11-01
• First posted: 2017-08-31
• Last updated: 2024-02-28

Locations

1 site across 1 country: Turkey (Türkiye)